Sankara Nethralaya Medical Research Foundation has organized South East Asia Glaucoma Interest Group Conference where the thought of retinal neuronal dysfunction through glaucoma was discussed. They also provided a future direction for glaucoma therapy by prevention or delay or reverse decay of the retinal ganglion cells and axons. The organizers found that results of genomics and proteomics will play a vital role in early detection of glaucoma. Stem cells may help restore vision in patients who have glaucoma, by repopulating or rescuing damaged cells. Stem cells can also be used for terminal stages of glaucoma. A few of our ophthalmologists are already working in stem cell therapy. Gene therapy approach is applicable to either lower the intra ocular pressure or protecting retinal ganglion cells. This approach could reprogram the target cells by transferring genetic material into them, so that they lower intra ocular pressure physiologically.