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Second patent for VRF

The Vision Research Foundation was awarded its second patent by the Patent Office, Government of India on November 5, 2009. It is now recognized as the patentee (patent no. 236495) for an invention titled “A Seminested Polymerase Chain Reaction (PCR) method for Rapid Detection and Specific Identification of Mycobacterium chelonae.” Scientists at the Larsen & Toubro Microbiology Research Centre carried out the fundamental research for the institute’s second patent. In May 2009, VRF received its first patent for another invention, — Mycobacterium fortuitum — research for which was also carried out by the Microbiology department. Mycobacterium chelonae and Mycobacterium fortuitum belong to the rapid growers of mycobacteria.

This Sn PCR technique will serve as a rapid diagnostic test to detect the “signature sequence” of Mycobacterium chelonae directly from clinical specimens obtained from the diseased part or tissue within 8 -12 hours and thus helps in early institution of the specific therapy. The method is not only rapid and reliable but also more sensitive than the existing laboratory methods such as the conventional culture techniques (isolation by culture followed by species identification) which requires anywhere between 4 -6 weeks time. Its inventors are Dr. HN Madhavan, Dr. Lily Therese and Jasmine Therese.

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